Figure 7.

Minocycline activated the Notch1 signaling in CD4⁺ T cells after ICH. (a) Representative immunostaining images of CD4 and Notch1 in different groups. (b) CD4⁺ T cells were cultured in vitro with PBS, minocycline, hemoglobin + PBS, and hemoglobin + Mino to check the protein levels of Notch1 signal. (c) Quantification of protein levels of Notch1 signal in different groups.  ^{∗ ∗ ∗}P < 0.001,  ^{∗ ∗ ∗ ∗}P < 0.0001 vs. the T cell + OPCs group; ^####P < 0.0001 vs. the T cell+ OPCs+ hemoglobin group.