Table 1.
Baseline characteristics of Parkinson’s disease patients and normal controls.
| PD n = 190 | NC n = 203 | p value | |
|---|---|---|---|
| Male, n (%) | 115 (60.5) | 106 (52.2) | 0.09 |
| Age in years | 68.4 (9.3) | 66.8 (9.6) | 0.06 |
| Smoking pack-years median (IQR) | 0.00 (IQR 0–8.2) | 2.00 (IQR 0–13.1) | 0.05 |
| CCI, median (IQR) | 0.0 (IQR 0–1) | 0.0 (IQR 0–1) | 0.44 |
| Time from diagnosis to baseline in months, median (IQR) | 1.3 (IQR 0.6–1.9) | – | – |
| UPDRS motor score | 23.6 (11.4) | – | – |
| Motor subtype | – | – | |
| PIGD, n (%) | 81 (41.2) | – | – |
| Tremor, n (%) | 89 (46.3) | – | – |
| Indeterminate, n (%) | 22 (12.5) | – | – |
| Hoehn & Yahr stage, median (IQR) | 2.0 (IQR 1.5–2.5) | – | – |
| MADRS score, median (IQR) | 3.0 (IQR 1.0–8.0) | 0.0 (IQR 0.0–1.0) | <0.001 |
| MMSE score, median (IQR) | 28.0 (IQR 27.0–29.0) | 29.0 (IQR 28.0–30.0) | <0.001 |
Values are means (SD) if not otherwise indicated. Bold values are statistically significant p < 0.05.
PD Parkinson’s disease, NC normal controls, CCI Charlson Comorbidity Index, UPDRS unified Parkinson’s disease rating scale, MMSE mini-mental state examination, MADRS Montgomery–Åsberg depression rating scale, PIGD postural instability and gait disorder.