Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
SAR408701, NAB, DM4 and MeDM4 molecular weight
| Entity | Molecular weight (g/mol) |
|---|---|
| SAR408701 | 150,000* |
| NAB | 144,522 |
| DM4 | 780 |
| MeDM4 | 794 |
*SAR408701 molecular weight varies slightly as a function of DAR, but it was assumed that each drug conjugate contributed to a negligible amount of the global molecular weight. The 150,000 g/mol molecular weight used for SAR408701 was an average molecular weight determined for an ADC with three [linker-DM4] complexes attached to the antibody
