Table 1 –
Perinatal Factors and Demographics
| High-dose N=21 | Standard-dose N=25 | P value | |
|---|---|---|---|
|
Maternal variables
| |||
| Race | 0.50 | ||
| African American, n (%) | 7 (33) | 12 (48) | |
| White, n (%) | 12 (57) | 11 (44) | |
|
| |||
| Asian, n (%) | 1 (5) | 2 (10) | |
|
| |||
| Hispanic, n (%) | 1 (5) | 0 | |
|
| |||
| Maternal age, years | 30.8 ± 7.6 | 27.2 ± 6.8 | 0.10 |
|
| |||
| High school graduate, n (%) | 20 (95) | 23 (92) | 1 |
|
| |||
| Private insurance, n (%) | 14 (67) | 5 (20) | 0.01 |
|
| |||
| Single parent household, n (%) | 2 (10) | 6 (24) | 0.25 |
|
| |||
| Social Risk Index Score | 1.0 ± 1.3 | 1.8 ± 1.4 | 0.04 |
|
| |||
| Income-to-needs ratio | 2.7 ± 2.3 | 1.7 ± 1.6 | 0.08 |
|
| |||
| Family dysfunction score | 1.4 ± 0.5 | 1.5 ± 0.4 | 0.45 |
|
| |||
| Alcohol use, n (%) | 0 | 4 (16) | 0.11 |
|
| |||
| Illicit drug use, n (%) | 0 | 1 (4) | 1 |
|
| |||
| Antenatal steroids, n (%) | 18 (86) | 18 (72) | 0.31 |
|
| |||
| Chorioamnionitis, n (%) | 8 (38) | 12 (48) | 0.56 |
|
| |||
| Vaginal delivery, n (%) | 7 (33) | 7 (28) | 0.76 |
|
| |||
| Infant variables | |||
|
| |||
| Gestational age at birth, weeks | 26.1 ± 2.1 | 27.1 ± 1.9 | 0.11 |
|
| |||
| Birth weight, grams | 817 ± 230 | 995 ± 250 | 0.02 |
|
| |||
| Growth restriction (weight z-score < −2 SD), n (%) | 3 (14) | 1 (4) | 0.32 |
|
| |||
| Growth restriction (OFC z-score < −2 SD), n (%) | 4 (19) | 0 | 0.04 |
|
| |||
| Male sex, n (%) | 10 (48) | 11 (44) | 1 |
|
| |||
| CRIB score | 5.0 ± 4.4 | 3.4 ± 3.3 | 0.17 |
OFC, occipitofrontal circumference
Values represent mean ± standard deviation unless otherwise indicated