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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Hypertension. 2022 Apr 18;79(6):1227–1236. doi: 10.1161/HYPERTENSIONAHA.121.18734

Figure 4. AT1aR suppresses renal dendritic cell (DC) activation during hypertension.

Figure 4.

Flow cytometric assessment of co-stimulatory molecule expression on CD11c+MHCIIhi DCs isolated from the kidney after 4 weeks of Ang II infusion. (A) Gating strategy for parsing for CD40, CD80, or CD86 positivity on DCs in the kidney, based on “fluorescence minus one” strategy. (B) Representative flow plots and the absolute number of CD11c+MHCIIhi Cells from WT and DC AT1aR KO groups. (C-E) Representative flow plots and the absolute number of (C) CD40+, (D) CD80+, and (E) CD86+ DCs from WT and DC AT1aR KO mice. N≥10 mice/group. Data are mean ± SE.