Skip to main content
. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Hypertension. 2022 Apr 18;79(6):1227–1236. doi: 10.1161/HYPERTENSIONAHA.121.18734

Figure 5. Mice lacking AT1aR on CD11c+ cells have augmented expression of inflammatory mediators in renal mononuclear cells.

Figure 5.

(A) Kidneys from hypertensive WT and DC AT1aR KO mice were harvested, and CD11c+MHCIIhi DCs were sorted for analysis of CCR7 and CCL5 mRNA expression. (B-C) Renal lymph nodes were harvested from WT and DC AT1aR KO mice at 4 weeks of Ang II, and CD4+ T cells and CD8+ T cells were isolated for RNA extraction. qPCR for mRNA levels of CCR7 and TNF-α in (B) CD4+ T cells and (C) CD8+ T cells. N≥3 mice/group. Data are mean ± SE.