Skip to main content
. Author manuscript; available in PMC: 2023 May 11.
Published in final edited form as: Chem Rev. 2022 Mar 11;122(9):8884–8910. doi: 10.1021/acs.chemrev.1c00773

Figure 8. Key components for PG biogenesis in the elongasome and mature divisome of E. coli.

Figure 8.

Lipid II is synthesized in the inner leaflet of the cytoplasmic or inner membrane (IM) and colocalizes with both the elongasome (left) and divisome (right) complexes. The exact molecular architecture of the elongasome and divisome, as well as how they insert new material into the pre-existing PG layer, remain unknown. LpoA and LpoB are lipoproteins that are anchored to the outer membrane (OM). For simplicity, PG hydrolases that are known to associate with each complex and to be important for their correct activity are not shown.