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. Author manuscript; available in PMC: 2022 Oct 18.
Published in final edited form as: Pediatr Res. 2021 Nov 13;92(3):712–720. doi: 10.1038/s41390-021-01832-9

Figure 4: Inflammatory and synaptic plasticity genes affected by PIA.

Figure 4:

Selected genes from the (A) STAT1 pathway and (B) CREB1 pathway were selected for confirmatory qPCR analyses along with other common inflammatory genes. Percentage difference from NBCs and p values are summarized in panel (C). Color intensity increases for increased difference. There was increased dysregulation after 25%, indicating a threshold response for males. Females showed a dose-dependent response to hematocrit for most genes at 18%.