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. 2022 Feb 15;11(2):529–543. doi: 10.1007/s40122-022-00361-5

Table 4.

NRS cough (NRS, numerical rating scale 0–10) in the three study groups (DEX group: dexmedetomidine, LIDO group: lidocaine and CONTROL group: normal saline) at 48 h and NRS scores across the three time points for each intervention group

Group NRS
Mean ± SD p value (DEX-CONTROL) p value (LIDO-CONTROL) p value (DEX-LIDO)
NRS cough 48 h
 LIDO 4.60 ± 2.62 1.0 1.0 1.0
 DEX 4.19 ± 2.94
 CONTROL 4.35 ± 2.37
NRS 3 months
 LIDO 1.84 ± 2.15 0.018* 0.79 0.68
 DEX 1.08 ± 1.47
 CONTROL 2.52 ± 2.18
NRS 6 months
 LIDO 0.84 ± 1.34 0.27 0.84 0.99
 DEX 0.46 ± 0.72
 CONTROL 1.48 ± 1.66
NRS 12 months
 LIDO 0.40 ± 1.04 0.95 0.99 1.00
 DEX 0.21 ± 0.66
 CONTROL 0.72 ± 1.06

Values are expressed as mean ± standard deviation (SD)

*Statistical significance (p < 0.05)