Cognitive impairment is a growing burden for healthcare systems, as a consequence of the increased aging of populations.

Frequently elderly people have concomitant health problems, with high prevalence of chronic pain.

Management of chronic pain in multimorbid patients with cognitive impairments is not an easy task, especially when the use of opioids is necessary.

This review points out many problems that physicians in charge of the care of elderly people with cognitive impairment are requested to deal with while caring for those patients.