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. 2022 Apr 18;11(2):667–681. doi: 10.1007/s40122-022-00386-w

Table 1.

General characteristics of all enrolled cancer patients (n = 186)

Opioid group (n = 86) Control (n = 100) p value
Age, years 55.74 ± 9.91 56.86 ± 8.35 0.41
Sex 0.64
 Female 24(28%) 31(31%)
 Male 62(72%) 69(69%)
Cancer type
 Lung cancer 39(45%) 52(52%) 0.37
 Liver cancer 12(14%) 7(7%) 0.12
 Gastric cancer 11(13%) 12(12%) 0.87
 Colorectal cancer 9(10%) 12(12%) 0.74
 Pancreatic cancer 7(8%) 8(8%) 0.97
 Esophageal cancer 4(5%) 5(5%) 0.91
 Other 4(5%) 4(4%) 0.83
Cancer staging
 I 1(1%) 1(1%) 0.91
 II 2(2%) 3(3%) 0.78
 III 17(20%) 25(25%) 0.39
 IV 66(77%) 71(71%) 0.38
ECOG
 0 12(14%) 20(20%) 0.28
 1 65(76%) 76(76%) 0.95
 2 9(10%) 4(4%) 0.08
Body mass index (BMI, kg/m2) 21.42 ± 3.06 22.22 ± 2.64 0.06
Total protein (g/l) 66.05 ± 7.61 68.02 ± 6.57 0.06
Pain management
 Oxycodone 86(100%) NA NA
 Dose (mg/day) 28.95 ± 22.96 NA NA
 Usage days 27.64 ± 30.02 NA NA

There were no significant differences in age, gender, tumor type and stage, ECOG score, BMI, and total protein between the two tumor groups. Data are presented as the mean ± SD or n (%)

NA not applicable

p values are for comparisons between the opioid and control group