TABLE 2.
No | PMID | Cancer type | Group | Drug | Responder | Non-Responder | Log2 (fold change) | p value |
---|---|---|---|---|---|---|---|---|
1 | 26997480 | Melanoma | All | Anti-PD-1 (pembrolizumab and nivolumab) | 14 | 12 | −0.215 | 0.695 |
MAPKi | Anti-PD-1 (pembrolizumab and nivolumab) | 6 | 5 | 0.735 | 0.665 | |||
Non-MAPKi | Anti-PD-1 (pembrolizumab and nivolumab) | 8 | 7 | −0.903 | 0.461 | |||
2 | 28552987 | Urothelial cancer | All | Anti-PD-L1 (atezolizumab) | 9 | 16 | 0.648 | 0.213 |
Smoking | Anti-PD-L1 (atezolizumab) | 5 | 9 | 0.192 | 0.872 | |||
Non-smoking | Anti-PD-L1 (atezolizumab) | 4 | 7 | 1.213 | 0.329 | |||
3 | 29033130 | Melanoma | All | Anti-PD-1 (nivolumab) | 26 | 23 | 0.609 | 0.276 |
NIV3-PROG | Anti-PD-1 (nivolumab) | 15 | 11 | 0.845 | 0.355 | |||
NIV3-NAIVE | Anti-PD-1 (nivolumab) | 11 | 12 | 0.403 | 0.673 | |||
4 | 29301960 | Clear cell renal cell carcinoma | All | Anti-PD-1 (nivolumab) | 4 | 8 | 2.049 | 0.114 |
VEGFRi | Anti-PD-1 (nivolumab) | 2 | 0 | 0 | 1 | |||
Non-VEGFRi | Anti-PD-1 (nivolumab) | 2 | 8 | 1.363 | 0.503 | |||
5 | 29443960 | Urothelial cancer | All | Anti-PD-L1 (atezolizumab) | 68 | 230 | −0.065 | 0.64 |