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. 2022 May 12;12:7909. doi: 10.1038/s41598-022-12117-4

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Receiver operating characteristic curve for intensive care unit mortality. At baseline, BAL NGAL (AUC 0.768, 95% CI 0.643–0.866, p < 0.001) and serum NGAL (AUC 0.747, 95% CI 0.621–0.849, p < 0.001) levels showed fair predictive power. SOFA score (AUC 0.684, 95% CI 0.554–0.796, p = 0.007) also showed significant predictive power. Baseline NGAL levels showed comparable predicted power compared to SOFA scores (serum P = 0.463, BAL p = 0.247). In addition, serum NGAL showed a predicted power comparable to that of BAL NGAL (p = 0.758). AUC area under the curve, BAL bronchoalveolar lavage, NGAL neutrophil gelatinase-associated lipocalin, APACHE II Acute Physiology and Chronic Health Evaluation II, SOFA sequential organ failure assessment.