Table 1.
Clinicopathologic features of the sample.
| N | % | |
|---|---|---|
| BRCA | ||
| BRCA1 | 16 | 30.8 |
| BRCA2 | 36 | 69.2 |
| Gender | ||
| Male | 5 | 9.6 |
| Female | 47 | 90.4 |
| Hairs | ||
| Blond | 9 | 17.3 |
| Brown | 35 | 67.3 |
| Black | 8 | 15.4 |
| Eyes | ||
| Blue | 15 | 28.8 |
| Brown | 33 | 63.5 |
| Black | 4 | 7.7 |
| FP | ||
| I | – | – |
| II | 16 | 30.8 |
| III | 36 | 69.2 |
| IV | – | |
| PCH | ||
| Negative | 29 | 55.8 |
| Positive* | 26 | 44.2 |
| CA | ||
| Negative | 37 | 71.2 |
| Positive** | 7 | 13.5 |
| Unknown | 6 | 11.5 |
| CL | ||
| None | 24 | 46.2 |
| Positive | 28 | 53.8 |
| eCAs | ||
| Negative | 28 | 53.8 |
| Positive | 24 | 46.2 |
| TN | ||
| >10 | 40 | 76.9 |
| ≤ 10 | 12 | 23.1 |
| Patterns of nevi ≠ | ||
| R | 1.272 | 63 |
| MC | 383 | 19.2 |
| MP | 193 | 9.6 |
| G | 115 | 5.7 |
| U | 54 | 2.7 |
FP means Fitzpatrick's phototype;
Positive personal cancer history (PCH): 18 breast cancer, 4 ovarian cancer, 1 prostate cancer;
Positive cutaneous anamnesis (CA): actinic keratosis 1, basal cell carcinoma 1, atopic dermatitis 1, dermatofibroma 1, granuloma annulare 1, lipoma 1, prurigo 1, dysplastic nevus, unknown 6; cutaneous lesions identified during the visit CL: seborrheic keratosis 14, sebaceous hyperplasia 1, warts 2, dermatofibroma 2, skin tags 2, acne 2, microcystic lymphatic hyperplasia 1, lentigo 1, melanonychia 1, eruptive cherry angiomas 24, in situ melanoma 1, dysplastic nevus 1; TN means total number of nevi, with a mean number of nevi of 38 (standard deviation: 25.7). Regarding the patterns of nevi: uniform globular pattern (G), reticular pattern (R), mixed pattern composed of a central globular or structureless area surrounded by a network (MC), mixed pattern composed of a central network or structureless brown-gray area surrounded by a peripheral rim of small brown globules (MP), and unspecified pattern (U).
The analysis of the patterns of nevi was performed on a total of 2.020 melanocytic lesions that were evaluated in all 52 patients.