Table 1.
Demographic and clinical characteristics of the study groups on day 1.
| Variables | Melatonin group Day 1 |
Control group Day 1 |
P-value Day 1 |
|---|---|---|---|
| Age (years) | 61.27 ± 18.09 | 65.35 ± 19.30 | 0.376 |
| Sex (male) | 19 (57.6) | 24 (70.6) | 0.316 |
| BMI ([kg/cm]2) | 26.66 + 5.32 | 25.52 + 4.71 | 0.46 |
| WBC (×1000/μL) | 11.41 ± 4.24 | 12.66 ± 4.37 | 0.241 |
| Neutrophil (×1000/μL) | 9630 ± 3810 | 11,010 ± 4170 | 0.199 |
| Lymph (×1000/μL) | 880 ± 530 | 1050 ± 420 | 0.173 |
| Neutrophil/lymph | 14.18 ± 7.10 | 11.91 ± 5.73 | 0.190 |
| Platelet (×1000/μL) | 221.36 ± 123.03 | 208.88 ± 87.94 | |
| Urea (mg/dL) | 70.94 ± 43.99 | 50.12 ± 23.30 | 0.019 |
| Cr (mg/dL) | 1.25 ± 0.54 | 1.14 ± 0.46 | 0.401 |
| ALT (U/L) | 65.03 ± 60.75 | 62.20 ± 67.21 | 0.871 |
| AST (U/L) | 58.21 ± 35.48 | 56.37 ± 50.44 | 0.871 |
| CRP (mg/L) | 62.73 ± 67.04 | 64.55 ± 55.15 | 0.913 |
| ESR (mm/h) | 47.66 ± 27.59 | 55.40 ± 38.80 | 0.507 |
| APACHE score | 19.6 ± 3.35 | 18.9 ± 4.43 | 0.682 |
| GCS | 7.62 ± 3.95 | 7.93 ± 3.19 | 0.721 |
BMI: Body mass index, WBC: white blood cells, Lymph: lymphocytes, Cr: serum creatinine, ALT: alanine aminotransferase, AST: aspartate aminotransferase, CRP: C-reactive protein, ESR: erythrocyte sedimentation rate, APACHE: Acute Physiology and Chronic Health Evaluation, GCS: Glasgow Coma Scale.