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. 2022 Apr 29;13:851391. doi: 10.3389/fgene.2022.851391

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Copyright © 2022 Ding, Zhang, Luo, Wu, Lin, Liang and Xue.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Revealing LUAD-related risk signature genes based on the risk model. (A) ceRNA for prognosis-related mRNA involved in the PI3K/Akt signaling pathway. (B) Univariate Cox regression analysis of the seven DE-mRNAs regulated by LINC01128. (C) Low-risk group had a longer OS than the high-risk group. (D) Expression levels of four signature genes of patients in the low-risk group and high-risk group. (E) Number of patients in the two groups is ranked by the risk score and the survival time of patients in the TCGA data set, respectively. (F) ROC analysis of the LUAD-related risk signature genes in the first 5 years.