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. 2022 May 13;11(1):67. doi: 10.1186/s43088-022-00251-x

Table 1.

Statistical analysis of results of comparison of LAMP with PCR and blood smear examination using MedCalc's Diagnostic test evaluation calculator

TEST PCR Blood smear
LAMP Positive Negative Total Positive Negative Total
Positive 23 4 27 16 11 27
Negative 0 73 73 0 73 73
Total 23 77 100 16 84 100
Statistics Value 95% confidence interval Value 95% confidence interval
Sensitivity 100.00% 85.18–100.00% 100.00% 79.41–100.00%
Specificity 94.81% 87.23–98.57% 86.90% 77.78–93.28%
Positive likelihood ratio 19.25 7.41–49.98 7.64 4.40–13.25
Negative likelihood ratio 0.00 0.00
Disease prevalence 23.00% 215.17–32.49% 16.00% 9.43–24.68%
Positive predictive value 85.19% 68.89–93.72% 59.26% 45.61–71.62%
Negative predictive value 100.00% 100.00%
Accuracy 96.00% 90.07–98.90% 89.00% 81.17–94.38%
Kappa 0.894 0.680
S.E. of kappa 0.052 0.086
95% confidence interval 0.792 to 0.995 0.511 to 0.849