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. 2022 Apr 29;16:863793. doi: 10.3389/fnins.2022.863793

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Copyright © 2022 Talifu, Qin, Xin, Chen, Liu, Dangol, Ma, Gong, Pei, Yu, Li and Du.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression of 5-HT2AR in spinal motoneurons. (A) Immunofluorescence staining of 5HT-2CA and ChAT in the spinal cord of rats from different groups. (B) Co-localization density of 5-HT2AR and motoneurons, n = 6 SCI-N + I group, n = 3 in SCI group, and n = 4 in the sham group (130 ChAT-positive neurons in eight visual fields in the sham group, 96 ChAT-positive neurons in six visual fields in the SCI group, 292 ChAT-positive neurons in 17 visual fields in the SCI-N + I group). *Represents the significance of the difference between groups (one-way ANOVA, Bonferroni’s post hoc test). One, two, and three symbols indicate P < 0.05, P < 0.01, and P < 0.001, respectively.