. Author manuscript; available in PMC: 2022 May 13.

Published in final edited form as: J Pediatr Urol. 2020 Nov 4;17(1):100.e1–100.e10. doi: 10.1016/j.jpurol.2020.11.001

Table 2. Contractile characteristics of detrusor muscle from normal and posterior urethral valve (PUV) bladders.

Mean data±SEM, except Elastic Modulus data as medians [25,75%] interquartiles; numbers in parenthesis are n preparations from N biopsy samples. Atropine resistance, % pre-atropine value

	Normal	PUV
T_max,EFS, mN.mm⁻²	8.0 ± 2.4 (12,9)	3.7 ± 1.2 (9,7) ^**
f_1/2, Hz	13.2 ± 2.2 (12,9)	17.9 ± 1.8 (8,7)
Atropine resistance, %	27.1 ± 3.7 (11,8)	21.6 ± 8.4 (6,6)
T_max,carb mN.mm⁻²	19.4 ± 4.3 (11,8)	11.2 ± 4.3 (8,7) ^*
Carbachol pEC₅₀	5.81 ± 0.12 (11,8)	5.72 ± 0.09 (7,7)
T_ABMA, mN.mm⁻²	11.1 ± 2.5 (11,8)	3.3 ± 1.5 (8,7) ^**
T_max,n-m/T _max,carb	0.46 ± 0.09 (10,7)	0.51 ± 0.08 (7,7)
SM/CT ratio	3.15 ± 0.64 (11,11)	1.02 ± 0.22 (8,8) ^***
Elastic modulus, kPa	25.6 [22.4,32.9] (6,6)	57.3 [38.0,77.7] (6,6) ^*

pEC₅₀ = -logEC₅₀; SM/CT = smooth muscle/connective tissue ratio.

p<0.05;

^**

p<0.01;

^***

p<0.001.