TABLE 4.
Cytotoxicity of compounds 1–14 (IC50, μM).
MGC-803 | MCF-7 | CNE-1 | |
---|---|---|---|
1 | 68.54 ± 0.33 | >100 | >100 |
2 | 34.14 ± 0.88 | 14.79 ± 1.22 | 13.75 ± 1.87 |
3 | >100 | >100 | >100 |
4 | 12.30 ± 0.61 | 8.04 ± 0.63 | 8.86 ± 0.22 |
5 | >100 | >100 | >100 |
6 | 58.40 ± 5.08 | 34.80 ± 3.50 | 31.65 ± 2.25 |
7 | 48.24 ± 4.42 | >100 | 35.58 ± 1.81 |
8 | 3.96 ± 1.78 | 93.08 ± 3.62 | >100 |
9 | 12.89 ± 4.98 | 7.49 ± 0.07 | 2.14 ± 0.39 |
10 | >100 | >100 | >100 |
11 | 46.54 ± 1.94 | >100 | 55.32 ± 3.32 |
12 | >100 | >100 | >100 |
13 | 2.48 ± 0.48 | 3.24 ± 0.35 | 1.44 ± 0.31 |
14 | 9.99 ± 2.79 | 46.93 ± 2.55 | 5.99 ± 0.50 |
Taxol | 0.56 ± 0.09 | 1.49 ± 0.22 | 2.72 ± 0.19 |