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. 2022 May 7;28(17):1781–1797. doi: 10.3748/wjg.v28.i17.1781

Table 3.

Correlation between heparin binding epidermal growth factor expression and clinicopathological characteristics of colorectal cancers in cohort of human colorectal cancer tissues

Clinicopathological variables Cohort tumor HB-EGF expression
P value
Negative (n = 26)
Positive (n = 39)
Age (yr) 65.72 (10.37) 69.43 (7.98)
Gender Female 11 23 > 0.05
Male 14 16
Size of tumor (mm) ≤ 10 5 7 > 0.05
> 10 21 32
Lymphatic metastasis Absent 19 19 > 0.05
Present 7 20
Tumor differentiation I-II 12 24 > 0.05
III-IV 14 15
TNM stage I-II 11 8 > 0.05
III-IV 15 31
AJCC clinical stage according to 7th issue 1 and 2A 17 24 > 0.05
3 and 3B 9 15

HB-EGF: Heparin binding epidermal growth factor; AJCC: American Journal of Critical Care.