NCT03604341.

Methods	"Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment"
Participants	"Inclusion Criteria: Aged 21 years or older Consented for elective medical abortion Pregnancy with intrauterine gestational sac up to 10 0/7 weeks, dated by ultrasound Able and willing to receive text messages via phone English speaking Able and willing to give informed consent and agree to the study terms Have assistance at home; no motor vehicle use while taking study medications Exclusion Criteria: Desires to continue pregnancy or currently breastfeeding Lack of access to cell phone and texting capabilities Prior participation in this study Early pregnancy failure Contraindications to the study medications: Marinol or marijuana derivatives, sesame oil, Ibuprofen Contraindications to medical abortion with Mifepristone or Misoprostol History of methadone, buprenorphine or heroin use within the last year History of a seizure disorder Used marijuana 5 or more days in the last week History of any adverse effects associated with prior use of recreational or medical marijuana products, or sensitivity/allergy to Marinol"
Interventions	"Drug: Dronabinol 5mg Cap Subjects randomized to Dronabinol 5mg Cap and ibuprofen 800mg for pain Other Name: Dronabinol Other: Placebo Subjects randomized to placebo and ibuprofen 800mg for pain"
Outcomes	"Maximum Self‐reported Pain Score on a Numeric Rating Scale [ Time Frame: 24 hours after misoprostol administration ] Women will text responds to surveys within 24 hours after misoprostol administration indicating their maximum self‐reported pain using an 11‐point numeric rating scale (NRS 0‐10) where 0=no pain and 10=worst possible pain."
Notes