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. Author manuscript; available in PMC: 2022 May 13.
Published in final edited form as: Acc Chem Res. 2021 Oct 22;54(21):3991–4000. doi: 10.1021/acs.accounts.1c00498

Figure 10. Bacteria typing.

Figure 10.

(A) Pathogen-specific detection keys (HAI keys) were prepared, targeting variable 16S rRNA region. Escherichia probe is shown as an example. (B) Specificity of HAI keys. The signal was high only in the presence of the target species ([E. coli] = 106 CFU/mL) even in the mixture of other bacterial species (106 CFU/mL per each). (C) Heat-map (Δr) showing the detection of five pathogens. (D) AMR keys identified HA-MRSA and CA-MRSA by targeting the specific regions in mecA and PVL genes. The heat-map and bar graphs display mean and mean ± s.d. (triplicates), respectively. Adapted with permission from ref 3. Copyright 2016 © The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science.