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US treatment increases the expression of c-Fos in the PFC of healthy mice. Representative images of c-Fos in the PFC after sham US (A) and US (B) for 30 min (nuclei: blue; c-Fos: red). (C) The amount of c-Fos protein in the US-treated group (n = 6) is significantly greater than that in the sham group (n = 4). US, ultrasound stimulation; PFC, prefrontal cortex; LPS, lipopolysaccharide. **p < 0.01.
