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. 2022 May 4;11(9):2576. doi: 10.3390/jcm11092576

Table 1.

Summary of eligible studies and their main findings. Values are given as mean (range) unless mentioned otherwise.

Author/Setting/Year Number of Patients
(% Women)
Age
(Years)
Preoperative Curve Final Curve Length of Follow-Up
(Years)
Complications
(%)
Main Findings/Conclusion
Abdullah [35]/Multi-center register study/2021 120 (84.2%) 12.6 (8.2–15.7) 51.2 (40–70) 27.5 (−5–52) 2 15.8 Higher than expected complication rate during learning curve.
Alanay [28]/Single-center/2020 42 (95.2) 12.1 (SD 1.5) 47 (35–68) 17 (−6–28) 2.8 7.1 Curve behavior after VBT varied according to Sanders stage.
Baker [36]/Single-center/2021 17 (70.6) 12.9 (SD 1.4) 45 (35–60) 20 (−40–25) 2 23.5 The majority of patients (53%) were successful despite four revisions and nine broken tethers.
Baroncini [31]/2 centers/2021 86 (83.7) 13.2 (SD 2.4) 52.4 (SD 13.9) 26.6 (SD 12.7) 2 8.1 The majority of the patients had a physiologic sagittal profile after surgery.
Bernard [37]/Single center/2022 20 (95.0) 13.8 (9–17) 56.5 (40–79) 19.4 (−17–56) 5.4 15 High success rate (95%) in helping children avoid fusion at five years post-surgery.
Betz [38]/Single center/2019 71 (83.1) 14.5 N/A N/A 2 4.2 Results of showed clinical success in 93% of immature patients, 81% of maturing, and 86% of mature patients.
Buyuk [39]/ Single center/2021 32 (93.8) 13 (11–15) 51 (42–70) 26 (7–43) 1 9.4 Particularly, sagittal plane motion was preserved postoperatively after anterior vertebral body tethering.
Cebeci [40]/ Single center/2017 12 (100) 12.2 (11–13) 46 (35–59) 18 (6–26) 2 0 VBT resulted in a significant correction in both major and compensatory curves.
Costanzo [41]/Single center/2022 23 (82.6) 12 (9–14) 56.5 (33–79) 37 (15–58) 2 8.7 Initial results were encouraging.
Hegde [30]/Single center/2021 10 (100) 14.9 (12–17) 52 (42–80) 15.3 (3–28) 2 0 Preliminary experience was promising.
Mackey [42]/Multicenter/2022 37 (97.3) 11.3 (IQR 10.9–11.8) 50 (IQR 43.5–58) 28 (IQR 21–35) 3 27 Satisfactory curve control and improved thoracic and spinal height.
Miyanji [27]/Multicenter/2020 57 (94.7) 12.7 (8.2–16.7) 51 (31–81) 23 (−18–57) 3.4 28.1 Satisfactory curve correction and an acceptable complication rate in skeletally immature patients.
Mladenov [43]/Single center/2021 20 (70.0) 13.4 (11.5–14.5) 46.5 (29–64) 23 (8–38) 1.6 5 Anticipated curve correction averaged 50%.
Newton [44]/Single center/2020 23 (69.6) 12 (9–15) 53 (41–67) 33 (−5–62) 3.4 39.1 AVBT resulted in less deformity correction and more revision procedures than PSF, but resulted in the delay or prevention of PSF in the majority of patients.
Pehlivanoglu [45]/Single center/2020 21 (71.4) 11.1 (9–14) 48.2 (IQR 44–52.1) 10.1 (IQR 7.7–11.2) 2.3 9.5 AVBT was a safe and effective option in skeletally immature patients with AIS.
Rushton [46]/2 centers/2021 112 (92.9) 12.7 (8.2–16.7) 50.8 (31–81) 25.7 (−32–58) 3.1 22 Satisfactory deformity correction in majority of cases.
Samdani [47]/Single center / 2021 57 (86.0) 12.4 (10.1–15.0) 40.4 (SD 6.8) 18.7 (SD 13.4) 4.6 12.3 Our current study suggested VBT as a viable option for skeletally immature children with scoliosis.
Takahashi [24]/ Single center / 2021 23 (69.6) 12.2 (SD 1.6) 53 (SD 8) N/A 3.4 30.4 Correction occurred primarily within 2 to 3 years after surgery.
Wong [48]/Single center/2019 5 (100) 12 (9–12) 40.1 (37.2–44.0) 25 (−12.4–58) 4 40 Of all patients, 60% avoided spinal fusion.
Yucekul [49]/Single center/2021 28 (82.1) 12.2 (10–14) 46 (SD 7.7) 12 (SD 11.5) 3.2 28.6 Intermediate discs and facet joints were preserved after growth modulation with VBT surgery.

IQR—interquartile range, N/A—not available, and SD—standard deviation.