Table 5.
Effects of fumonisins intoxication on the chemical coding of the rat duodenal enteric neurons (mean ± SD).
| Parameter | Group | p-Value | ||
|---|---|---|---|---|
| Control | FB60 | FB90 | ||
| VIP-IR myenteric neurons | 11.61 ± 1.61 a | 15.14 ± 2.35 b | 17.65 ± 4.10 b | 0.008 |
| VIP-IR submucosal neurons | 24.84 ± 3.35 a | 27.46 ± 2.55 b | 30.23 ± 3.08 b | 0.024 |
| VIP-IR fibres | ||||
| Muscular layer | 0.48 ± 0.07 a | 0.58 ± 0.07 b | 0.66 ± 0.06 b | <0.001 |
| Submucosa | 0.23 ± 0.04 a | 0.30 ± 0.06 b | 0.32 ± 0.06 b | 0.041 |
| Mucosa | 0.43 ± 0.04 a | 0.77 ± 0.07 b | 0.81 ± 0.12 b | <0.001 |
| galanin-IR myenteric neurons | 21.05 ± 2.84 a | 27.47 ± 4.85 b | 30.02 ± 5.90 b | 0.014 |
| galanin-IR submucosal neurons | 19.21 ± 3.35 a | 25.97 ± 4.76 b | 27.06 ± 4.74 b | 0.014 |
| galanin-IR fibres | ||||
| Muscular layer | 0.83 ± 0.12 a | 0.94 ± 0.12 b | 1.11 ± 0.07 b | <0.001 |
| Submucosa | 0.13 ± 0.04 a | 0.23 ± 0.07 b | 0.25 ± 0.05 b | 0.004 |
| Mucosa | 0.12 ± 0.04 a | 0.17 ± 0.05 b | 0.19 ± 0.01 b | 0.017 |
Statistical significance: n.s.—not significant; Different letters indicate significant differences between groups.