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. 2022 May 4;14(9):1923. doi: 10.3390/nu14091923

Table 1.

Absorption mechanisms of dietary carbohydrates and specific drugs available to facilitate digestion.

Carbohydrate Type Absorption Mechanisms Available Specific Drugs
Monosaccharides Fructose Absorption of excess fructose occurs in the small intestine: rapidly via GLUT-2, the sodium-dependent active transport mechanism in conjunction with glucose; slowly via GLUT-5, a specific transporter for fructose using carrier-mediated facilitated diffusion. Thus, fructose is well-absorbed in the presence of equimolar glucose in the proximal small intestine, whereas free fructose is absorbed slowly along the length of the small intestine. Xylose-isomerase
Disaccharides Lactose


Sucrose
Unabsorbed in small intestine if lactase is absent.
Unabsorbed in small intestine in case of sucrase-isomaltase deficiency
Lactase


Sacrosidase
Oligosaccharides FOS *
GOS
Humans do not possess small intestinal hydrolases to hydrolyse oligosaccharides, and they are unabsorbed. None
Polyols Sorbitol Mannitol Maltitol Isomalt Lactitol Xylitol Sugar alcohols are poorly absorbed along the length of the small intestine by slow passive diffusion. None

* FOS: Fructo-oligosaccharides; GOS: Galacto-oligosaccharides.