Table 1.
Carbohydrate | Type | Absorption Mechanisms | Available Specific Drugs |
---|---|---|---|
Monosaccharides | Fructose | Absorption of excess fructose occurs in the small intestine: rapidly via GLUT-2, the sodium-dependent active transport mechanism in conjunction with glucose; slowly via GLUT-5, a specific transporter for fructose using carrier-mediated facilitated diffusion. Thus, fructose is well-absorbed in the presence of equimolar glucose in the proximal small intestine, whereas free fructose is absorbed slowly along the length of the small intestine. | Xylose-isomerase |
Disaccharides | Lactose Sucrose |
Unabsorbed in small intestine if lactase is absent. Unabsorbed in small intestine in case of sucrase-isomaltase deficiency |
Lactase Sacrosidase |
Oligosaccharides | FOS * GOS |
Humans do not possess small intestinal hydrolases to hydrolyse oligosaccharides, and they are unabsorbed. | None |
Polyols | Sorbitol Mannitol Maltitol Isomalt Lactitol Xylitol | Sugar alcohols are poorly absorbed along the length of the small intestine by slow passive diffusion. | None |
* FOS: Fructo-oligosaccharides; GOS: Galacto-oligosaccharides.