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. 2022 May 2;14(9):2273. doi: 10.3390/cancers14092273

Table 1.

Patients’ and treatment characteristics. BED10 = biologically effective dose (assuming an α/β ratio of 10); 3DCRT = 3-D conformal radiotherapy; 2DRT = 2-D radiotherapy; IMRT = intensity-modulated radiotherapy; VMAT = volumetric modulated arc therapy; Tomo = tomotherapy.

Patients’ Characteristics (Per Access)
Lines of Systemic Treatment before (Number and Percentage, Data Available for 409 Accesses)
Mean 1.65 Range 0–10
One line 42 (10.3%)
Two lines 65 (15.9%)
Three lines 38 (9.3%)
Four lines 28 (6.8%)
Five or more lines 43 (10.5%)
Number of Treated Lesions
Mean 1.41 Range 1–4
One lesion 274 (66.7%)
Two lesions 110 (26.8%)
Three or more 27 (6.6%)
Age at Start of Radiotherapy
Median 68.1 years Range 31.2–92.5 years
Treatment Characteristics (per Lesion)
Systemic Treatment Concurrent with Radiotherapy
No 220 (38.1%) Chemotherapy 76 (13.2%) Biologic treatment 281 (48.7%)
Type of concurrent biological systemic treatment
Lenalidomide or lenamide-containing combinations 76 (13.2%)
Bortezomib 67 (11.6%)
Bortezomib-containing combinations 117 (20.3%)
Other biological agents 21 (3.6%)
Site of treated lesions
Vertebral 346 (60%) Extremities 108 (18.7%) Pelvic bones 57 (9.9%)
Ribs/sternum 36 (6.4%) Skull 15 (2.6%) Other 15 (2.6%)
Radiotherapy BED10
Less than 15 Gy 42 (7.3%) 15–38 Gy 165 (28.6%) More than 38 Gy 370 (64.1%)
Radiotherapy schedules
30 Gy/10 fr 360 (62.4%) 20 Gy/5 fr 158 (27.4%) 8 Gy/1 fr 34 (5.9%)
Radiotherapy technique
3DCRT 440 (76.3%) 2DRT 117 (20.3%) IMRT/VMAT/Tomo 20 (3.5%)