Table 2.

Higher-grade toxicity reported during radiotherapy, at one month and at three months after the end of radiotherapy. RT = radiotherapy; CHT = chemotherapy; BED10 = biologically effective dose (assuming an α/β ratio of 10).

Higher-Grade Toxicity (Per n of Accesses)
During Radiotherapy (Data Available for 410 Accesses)
	G0	G1	G2	G3	G4	Total
Overall	242 (59%)	151 (36.8%)	13 (3.2%)	3 (0.7%)	1 (0.2%)	410
RT alone	101 (64.3%)	54 (34.4%)	1 (0.6%)	1 (0.6%)	0 (0%)	157
Concurrent CHT	22 (43.1%)	24 (47.1%)	3 (5.9%)	1 (2%)	1 (2%)	51
Concurrent biological agent	119 (58.9%)	73 (36.1%)	9 (4.5%)	1 (0.5%)	0 (0%)	202
BED10 < 15 Gy	28 (90.3%)	2 (6.5%)	0 (0%)	1 (3.2%)	0 (0%)	31
BED10 15–38 Gy	86 (71.7%)	30 (25%)	3 (2.5%)	0 (0%)	1 (0.8%)	120
BED10 > 38 Gy	128 (50.6%)	119 (45.9%)	10 (3.9%)	2 (0.8%)	0 (0%)	259
At 1 Month after Radiotherapy (Data Available for 267 Accesses)
	G0	G1	G2	G3	G4	Total
Overall	251 (94%)	14 (5.2%)	2 (0.7%)	0 (0%)	0 (0%)	267
RT alone	96 (92.3%)	7 (6.7%)	1 (1%)	0 (0%)	0 (0%)	104
Concurrent CHT	21 (100%)	0 (0%)	0 (0%)	0 (0%)	0 (0%)	21
Concurrent biological agent	134 (94.4%)	7 (4.9%)	1 (0.7%)	0 (0%)	0 (0%)	142
BED10 < 15 Gy	20 (100%)	0 (0%)	0 (0%)	0 (0%)	0 (0%)	20
BED10 15–38 Gy	67 (98.5%)	0 (0%)	1 (1.5%)	0 (0%)	0 (0%)	68
BED10 > 38 Gy	164 (91.6%)	14 (7.8%)	1 (0.6%)	0 (0%)	0 (0%)	179
At 3 Months after Radiotherapy (Data Available for 263 Accesses)
	G0	G1	G2	G3	G4	Total
Overall	254 (96.6%)	8 (3%)	1 (0.4%)	0 (0%)	0 (0%)	263
RT alone	99 (96.1%)	3 (2.9%)	1 (1%)	0 (0%)	0 (0%)	103
Concurrent CHT	20 (100%)	0 (0%)	0 (0%)	0 (0%)	0 (0%)	20
Concurrent biological agent	135 (96.4%)	5 (3.6%)	0 (0%)	0 (0%)	0 (0%)	140
BED10 < 15 Gy	18 (100%)	0 (0%)	0 (0%)	0 (0%)	0 (0%)	18
BED10 15–38 Gy	66 (100%)	0 (0%)	0 (0%)	0 (0%)	0 (0%)	66
BED10 > 38 Gy	160 (94.7%)	8 (4.7%)	1 (0.6%)	0 (0%)	0 (0%)	169