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. 2022 May 2;23(9):5058. doi: 10.3390/ijms23095058

Table 1.

Possible CSC phenotypes of breast cancer according to the literature data.

Phenotype Sources of Samples Source
ABCG2+ Cell line HCC1937 [49]
ANTXR1+ Mouse mammary metastatic tumor, cell line TMD231 [50]
CD29+ Cell line MCF-7 [51]
CD61+ Mouse mammary tumor MMTV-Wnt-1 [52]
CD133+ Primary human breast tumor; cell lines MDA-MB-231, MCF-7, ZR-75 [53,54]
CXCR4+ Metastatic breast cancer; cell line MCF-7; mouse cell lines 4T1, 4T07, 168Farn, 67NR [55]
PROCR+ Cell line MDA-MB-361; adipose tissue of the mammary gland of mice with MDA-MB-231 [56]
CD24+CD29+ Primary breast cancer BRCA1 mouse; mouse mammary tumor tissue MMTV-WNT1 [57]
CD24+CD49f+ BRCA1 mouse primary breast tumor [58]
CD44+CD24−/low Primary human breast tumor; cell lines MCF-7, BT-549, MDA-MB-231, MDA-MB-361, MDA-MB-468, T47D, ZR75, SK-BR-3, HCC1937 [44]
CD49fhiCD61hi Transgenic mouse model HER2/neu [59]
CD133+ALDH1+ Invasive ductal breast tumor [60]
CD44+CD24−/lowABCG2+ MDA-MB-231 and MCF-7 cell lines [61]
CD44+CD24−/lowALDH1+ Invasive ductal human breast cancer; cell lines MDA-MB-231, MDA-MB-453, MDA-MB-468, SUM149, SUM159, SK-BR-3, ZR-75, C 1954 [46,62]
CD44+CD24−/lowEpCAM+ Cell lines MCF-7, MDA-MB-231, SUM149 и SUM159 [42]
CD44+CD24−/lowSSEA-3+ MCF-7 and MDA-MB-231 cell lines [63]
CD44+CD49f+CD133/2+ Primary ER–human breast tumor [64]
CD44+CD133+ALDH1+/hi Cell line MDA-MB-468 [65]
CD133hiCXCR4hiALDH1hi Invasive ductal human breast cancer [66]
EpCAM+CD49f+ Aberrant human progenitor cells from BRCA1-mutant breast tissue [67]
EpCAMhiPROCRhiSSEA-3+ MCF-7 and MDA-MB-231 cell lines [63]
GD2+GD3+GD3Shi Cell lines MDA-MB-231 and MDA-MB-468 [68]