Table 1.

Frequency of the pathogenic variants in DDR genes shared by pancreatic and prostate cancers.

	Pancreatic Cancer				Prostate Cancer
	Germline [25,35,59,60]		Somatic [25,36,37,63]		Germline [48,61,62]		Somatic [61,63,64]
Gene	Range	Max	Range	Max	Range	Max	Range 1	Max
BRCA1/2	0.9–5	5	0.9–4.8	4.80	0.3–8.6	8.60	0.6–15.2	15.2
ATM	2–3.09		2.2–9		1.59–2.3		1.9–7.3
ATR	0.2				0.29
BRIP1	0.22–1		0.48–1		0.28–0.45
CHEK1-2	0.3–2.2		0.2–0.6		1.87–4.1		0.9–1.9
FANCA	1.04		0.6				3
MMR	0.39–1.2		0.8		0.14–1.7		3–6
NBN	0.2–0.59				0.29–2
PALB2	0.1–0.97		0.2–1.2		0.45–0.56		0.4–2
RAD50	0.3–0.36		0.5				1
RAD51	0.35 2				0.14–0.57 2,3		0.54 2,3
Non-BRCA1/2		11		13.7		12.07		21.74
TOTAL		16		18.5		20.67		36.94

Frequencies are reported as percentages. ¹ mCRPC, ² RAD51C, ³ RAD51D.