Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 28;11(9):1488. doi: 10.3390/cells11091488

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

CDN1163 increases endothelium-dependent and endothelium-independent relaxation of db/db mice in in vivo experiments. (A,B) Vascular relaxation of aortic rings isolated from control mice (A) (Ctrl+veh, n = 11; Ctrl+CDN, n = 9) or db/db mice (B) (Db+veh, n = 10; Db+CDN, n = 11) with ACh. (C,D) Vascular relaxation of aortic rings isolated from control mice (C) (n = 9 for each group) or db/db mice (D) (n = 9 for each group) with SNP. Results of relaxation are expressed as percentage changes in the steady-state level of contraction with 10^−6.5 mol/L L-phenylephrine. Error bars represent SEM. * p < 0.05 vs. Db+veh. CDN, CDN1163; Ctrl, control mice; Db, db/db mice; veh, vehicle; SNP, sodium nitroprusside.