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. 2022 Apr 27;11(9):2449. doi: 10.3390/jcm11092449

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Angiopoietin-like 4 (ANGPTL4) and interleukin 1-beta (IL-1β) expression is increased in the epicardial adipose tissue (EAT) of patients with coronary artery disease (CAD). (A–F) Comparison of the gene expression of ANGPTL and inflammatory cytokines in EAT in patients with or without CAD. Two-tailed unpaired Student’s t-tests were used to compare non-CAD and CAD subjects. (G,H) Comparison of ANGPTL4 mRNA expression in the EAT of patients with or without ARBs (G) and statins (H). (I) Linear regression analysis was performed in the combined groups of non-CAD and CAD subjects. R and p-values are shown in the Figure.