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Dose-dependent growth inhibition via gp130 inhibitor treatment in PDAC sphere cells. (A) PANC-1 and PK-1 cells were treated with SC144 at the indicated concentrations in triplicate for 7 days in 3D-culture conditions, and the ATP assay was performed to analyze the growth of sphere cells (* p < 0.05, ** p < 0.01 vs. control). (B) IC50 values were measured for each cell line following 7 days under 3D-culture conditions with various concentrations of SC144.
