Table 2.
Results of immunohistochemistry.
| Immunohisto-chemical Marker | Assessment | Carcinoma Overall |
Squamous Cell Carcinoma | Other Carcinoma | Thymoma Overall | A | B3 | MNTLS | p-Value a |
|---|---|---|---|---|---|---|---|---|---|
| n | 37 | 23 | 14 | 44 | 25 | 11 | 8 | ||
| BAP1 | n (%) cases with loss of expression | 4 (11.4) b | 1 (4.5) c | 3 (23.1) c | 0 (0.0) d | 0 (0.0) e | 0 (0.0) b | 0 (0.0) c | 0.05 |
| mTAP | 5 (14.7) f,g | 3 (13.6) c | 2 (16.7) b,g | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0.005 | |
| GLUT1, any staining | Median % positive tumor cells (range) | 90 (0–100) b | 90 (10–100) c | 40 (0–100) c | 1 (0–90) | 5 (0–80) | 30 (0–90) | 0 (0–1) | <0.0001 |
| GLUT1, membranous | 60 (0–100) h | 80 (0–100) b | 5 (0–100) b | 0 (0–90) b | 0 (0–5) b | 10 (0–90) | 0 (0–0) | <0.0001 | |
| CD5 | 5 (0–100) f | 40 (0–100) c | 0 (0–10) b | 0 (0–30) | 0 (0–30) | 0 (0–0) | 0 (0–1) | 0.0001 | |
| CD117 | 100 (0–100) b | 100 (0–100) | 60 (0–100) b | 0 (0–1) | 0 (0–1) | 0 (0–0) | 0 (0–0) | <0.0001 | |
| TdT | n (%) cases with more than rare thymocytes | 1 (2.8) i,c | 0 (0.0) i | 1 (7.7) c | 34 (77.3) k | 18 (72.0) i | 8 (72.7) l | 8 (100.0) | <0.0001 |
ap-value between carcinoma and all thymomas. Information not available for b 2; c 1; d 8; e 5; f 3; h 4 cases. g An additional carcinoma showed partial loss of expression of mTAP. i 2, k 3, or l 1 cases with rare thymocytes.