Table A4.
ExPH at ESE vs. continuous or categorical ultrasound parameters.
| Continuous Ultrasound Parameters | ExPH at ESE | Mean | SD | p-Value |
|---|---|---|---|---|
| LVEDD | no | 43.459 | 5.322 | 0.745 |
| yes | 44.083 | 6.445 | ||
| LVESD | no | 26.625 | 6.460 | 0.472 |
| yes | 25.000 | 7.058 | ||
| LVEDV | no | 100.938 | 31.460 | 0.992 |
| yes | 100.833 | 29.489 | ||
| iLVEDV | no | 35.857 | 10.955 | 0.568 |
| yes | 33.743 | 10.596 | ||
| LVESV | no | 36.406 | 14.555 | 0.752 |
| yes | 38.000 | 15.486 | ||
| iLVESV | no | 12.992 | 5.205 | 0.971 |
| yes | 13.054 | 4.604 | ||
| LV | no | 149.453 | 44.358 | 0.974 |
| yes | 149.967 | 51.515 | ||
| iLV mass | no | 77.544 | 28.061 | 0.593 |
| yes | 72.343 | 29.882 | ||
| LAD | no | 48.531 | 8.481 | 0.737 |
| yes | 47.625 | 6.057 | ||
| LAV | no | 38.844 | 19.955 | 0.276 |
| yes | 32.142 | 10.252 | ||
| iLAV | no | 13.895 | 7.507 | 0.290 |
| yes | 11.452 | 3.692 | ||
| LVEF | no | 66.459 | 7.437 | 0.157 |
| yes | 63.000 | 6.030 | ||
| FwSV | no | 73.022 | 24.849 | 0.155 |
| yes | 62.000 | 13.671 | ||
| iFwSV | no | 25.663 | 8.952 | 0.090 |
| yes | 20.957 | 4.347 | ||
| MR | no | 0.656 | 0.787 | 0.193 |
| yes | 0.333 | 0.492 | ||
| AO | no | 0.313 | 0.738 | 0.304 |
| yes | 0.083 | 0.289 | ||
| E wave | no | 68.084 | 18.606 | 0.284 |
| yes | 74.308 | 10.979 | ||
| A wave | no | 71.400 | 30.367 | 0.784 |
| yes | 74.158 | 26.943 | ||
| Septal e wave | no | 10.128 | 2.958 | 0.384 |
| yes | 9.317 | 1.908 | ||
| E/A | no | 1.037 | 0.397 | 0.415 |
| yes | 1.166 | 0.613 | ||
| E/e | no | 6.251 | 3.400 | 0.077 |
| yes | 8.129 | 1.778 | ||
| iRVESA | no | 4.083 | 1.862 | 0.492 |
| yes | 4.505 | 1.622 | ||
| iRVEDA | no | 7.029 | 2.113 | 0.708 |
| yes | 6.749 | 2.405 | ||
| iRVESV | no | 7.183 | 4.886 | 0.950 |
| yes | 7.278 | 3.001 | ||
| iRVEDV | no | 16.217 | 6.461 | 0.126 |
| yes | 13.058 | 4.326 | ||
| RD1 | no | 35.987 | 6.920 | 0.660 |
| yes | 37.042 | 7.344 | ||
| RD2 | no | 33.188 | 5.538 | 0.297 |
| yes | 31.092 | 6.712 | ||
| RD3 | no | 20.031 | 6.699 | 0.222 |
| yes | 17.342 | 5.520 | ||
| RVOT prox. | no | 31.119 | 5.782 | 0.505 |
| yes | 32.383 | 4.882 | ||
| RVOT dist. | no | 31.656 | 7.305 | 0.754 |
| yes | 30.900 | 6.468 | ||
| Eccentricity index | no | 0.943 | 0.112 | 0.335 |
| yes | 0.908 | 0.096 | ||
| RV/LV basal diameter ratio | no | 0.852 | 0.157 | 0.815 |
| yes | 0.839 | 0.179 | ||
| TAPSE | no | 21.707 | 6.949 | 0.495 |
| yes | 23.392 | 7.958 | ||
| FAC | no | 45.397 | 9.376 | 0.391 |
| yes | 48.167 | 9.609 | ||
| RV E/A | no | 4.333 | 13.319 | 0.391 |
| yes | 0.976 | 0.431 | ||
| RV E/e | no | 3.729 | 1.882 | 0.946 |
| yes | 3.774 | 1.739 | ||
| RV S vel | no | 10.950 | 4.497 | 0.561 |
| yes | 11.883 | 5.251 | ||
| RV S VTI | no | 3.174 | 3.328 | 0.867 |
| yes | 2.968 | 4.289 | ||
| TR | no | 1.313 | 0.471 | 0.077 |
| yes | 1.000 | 0.603 | ||
| sPAP | no | 22.344 | 6.003 | 0.794 |
| yes | 21.833 | 4.896 | ||
| sPAP at exercise peak | no | 30.909 | 8.846 | <0.001 |
| yes | 45.933 | 7.504 | ||
| mPAP | no | 16.351 | 3.802 | 0.991 |
| yes | 16.337 | 4.212 | ||
| TRV | no | 2.009 | 0.389 | 0.622 |
| yes | 2.075 | 0.409 | ||
| TRV at exercise peak | no | 2.472 | 0.502 | 0.048 |
| yes | 2.850 | 0.659 | ||
| RV outflow AT | no | 105.027 | 43.990 | 0.065 |
| yes | 132.000 | 36.352 | ||
| VCI diameter | no | 14.722 | 4.534 | 0.885 |
| yes | 14.942 | 4.191 | ||
| RA area | no | 14.253 | 3.127 | 0.008 |
| yes | 17.092 | 2.710 | ||
| iRAV | no | 5.266 | 2.186 | 0.189 |
| yes | 6.166 | 1.300 | ||
| VTI at rvot | no | 16.065 | 3.552 | <0.001 |
| yes | 10.575 | 2.703 | ||
| VRT/VTI at rvot | no | 0.153 | 0.143 | 0.289 |
| yes | 0.198 | 0.041 | ||
| TAPSE/PAPs | no | 1.024 | 0.321 | 0.448 |
| yes | 1.123 | 0.516 | ||
| Categorical ultrasound parameter | ExPH at ESE | no | yes | p-value |
| Concentric remodeling | no | 19 | 5 | 0.293 |
| yes | 13 | 7 | ||
| Normal geometry | no | 18 | 7 | 0.901 |
| yes | 14 | 5 | ||
| Concentric hypertrophy | no | 29 | 12 | 0.272 |
| yes | 3 | 0 | ||
| Eccentric hypertrophy | no | 31 | 12 | 0.536 |
| yes | 1 | 0 |
Abbreviations: ExPH, isolated exercise pulmonary hypertension; ESE, exercise stress echocardiogram; LVEDD, left ventricle end-diastolic diameter; LVESD, left ventricle end-systolic diameter; LVEDV, left ventricle end-diastolic volume; LVESV, left ventricle end-systolic volume; iLVEDV, indexed LVEDV; iLVESV, indexed LVESV; LAD, left atrial diameter; LAV, left atrial volume; iLAV, indexed LAV; LVEF, left ventricle ejection fraction; FwSV, forward stroke volume; iFwSV, indexed FwSV; iRVESA, indexed right ventricle end-systolic area; iRVEDA, indexed right ventricle end-diastolic area; iRVESV, indexed right ventricle end-systolic volume; iRVEDV, indexed right ventricle end-diastolic volume; RD, right diameter; RVOT, right ventricle outflow; TAPSE, tricuspid annular plane excursion; FAC, fractional area change; VTI, velocity time integral; sPAP, systolic pulmonary arterial pressure; mPAP, mean PAP; TR, tricuspid regurgitation; IVC, inferior vena cava, iRAV, indexed right atrial volume; TRV, tricuspid regurgitation velocity.