Table 3.

Thermodynamic parameters determined by isothermal titration calorimetry.

S70A-CTX-M-15	Kd (μM)	ΔH (cal mol−1)	ΔS (cal mol−1 K−1)	ΔG (kcal mol−1)
Clavulanic acid	288.6	−1333	11.7	−4.8
Nitrocefin	71.3	−2025	12.1	−5.7
Ceftiofur	38.2	−1157	16.3	−6.0
Ampicillin	28.8	−509	19.1	−6.2
DFC	10.7	−2246	15.2	−6.7