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. 2022 Apr 29;12:879423. doi: 10.3389/fcimb.2022.879423

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Copyright © 2022 Yang, Liu, Pang, Cai, Lin, Guo and Wei

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CLSM images of F. nucleatum subsp. polymorphum and S. gordonii infection of hGECs for 4 h F. nucleatum subsp. polymorphum and S. gordonii were stained green by CFSE. The cytoskeleton was stained red by phalloidin, and the nucleus was stained blue by DAPI. (A) Blank control group. (B) F. nucleatum subsp. polymorphum monoculture group (Fnp). (C) S. gordonii monoculture group (Sg). (D) F. nucleatum subsp. polymorphum and S. gordonii coinfection group (Fnp+Sg). (E) F. nucleatum subsp. polymorphum and S. gordonii coaggregation group (Fnp-Sg).