Table 8.
Summary of subjective and objective dry-eye parameters in patients who did not perform lid hygiene. (A) Summary of subjective symptoms of 1st and 2nd examination. (B) Summary of objective signs of 1st and 2nd examination.
| (A) | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DM 1–4 (N = 238) | DM-1 (N =103) | DM-2 (N = 83) | DM-3 (N = 31) | DM-4 (N = 21) | ||||||||||||
| Exam | Median | IQR | p | Median | IQR | p | Median | IQR | p | Median | IQR | p | Median | IQR | p | |
| SPEED (total) | 1st | 11.0 | 8.0 | 0.087 | 12.0 | 8.0 | 0.179 | 11.0 | 7.0 | 0.265 | 10.0 | 7.0 | 0.883 | 10.0 | 8.0 | 0.458 |
| 2nd | 10.0 | 8.0 | 10.0 | 8.0 | 11.0 | 8.0 | 10.0 | 9.0 | 7.0 | 7.0 | ||||||
| Frequency (SPEED) | 1st | 5.0 | 3.0 | 0.062 | 5.0 | 3.0 | 0.312 | 5.0 | 3.0 | 0.154 | 4.0 | 3.0 | 0.726 | 5.0 | 3.0 | 0.308 |
| 2nd | 4.5 | 4.0 | 5.0 | 4.0 | 5.0 | 2.0 | 4.0 | 4.0 | 4.0 | 3.5 | ||||||
| Severity (SPEED) | 1st | 6.0 | 4.0 | 0.149 | 6.0 | 4.5 | 0.155 | 6.0 | 4.0 | 0.437 | 5.0 | 5.0 | 0.980 | 5.0 | 5.0 | 0.726 |
| 2nd | 5.0 | 5.0 | 5.0 | 5.0 | 5.0 | 5.0 | 5.0 | 7.0 | 4.0 | 4.5 | ||||||
| OSDI(total) | 1st | 36.4 | 33.1 | 0.091 | 37.5 | 30.0 | 0.305 | 36.0 | 34.3 | 0.305 | 31.8 | 32.7 | 0.595 | 32.5 | 34.0 | 0.498 |
| 2nd | 31.3 | 31.5 | 31.3 | 38.9 | 31.8 | 27.5 | 32.5 | 22.2 | 29.2 | 24.9 | ||||||
| OSDI (A) | 1st | 8.0 | 6.3 | 0.093 | 8.0 | 6.5 | 0.180 | 8.0 | 8.0 | 0.506 | 7.0 | 7.0 | 0.498 | 7.0 | 8.0 | 0.539 |
| 2nd | 7.0 | 7.0 | 7.0 | 7.0 | 7.0 | 7.0 | 6.0 | 5.0 | 5.0 | 8.0 | ||||||
| OSDI (B) | 1st | 4.0 | 5.0 | <0.001 | 4.0 | 6.0 | 0.049 | 4.0 | 5.0 | 0.024 | 3.0 | 4.0 | 0.070 | 3.0 | 5.0 | 0.378 |
| 2nd | 3.0 | 5.0 | 4.0 | 5.0 | 3.0 | 3.0 | 3.0 | 4.0 | 2.0 | 3.5 | ||||||
| OSDI (C) | 1st | 3.0 | 5.0 | 0.727 | 3.0 | 5.5 | 0.881 | 3.0 | 5.0 | 0.841 | 3.0 | 5.0 | 0.381 | 3.0 | 5.0 | 0.324 |
| 2nd | 3.0 | 4.3 | 3.0 | 4.0 | 3.0 | 5.0 | 3.0 | 7.0 | 3.0 | 2.5 | ||||||
| (B) | ||||||||||||||||
| DM 1–4 (N = 238) | DM-1 (N =103) | DM-2 (N = 83) | DM-3 (N = 31) | DM-4 (N = 21) | ||||||||||||
| Exam | Median | IQR | p | Median | IQR | p | Median | IQR | p | Median | IQR | p | Median | IQR | p | |
| LLT (nm) | 1st | 69.0 | 33.0 | 0.368 | 66.0 | 28.0 | 0.797 | 69.0 | 29.0 | 0.244 | 77.0 | 38.0 | 0.748 | 86.0 | 48.0 | 0.370 |
| 2nd | 68.5 | 36.0 | 64.0 | 35.0 | 67.0 | 29.0 | 74.0 | 34.0 | 83.0 | 42.5 | ||||||
| MGE | 1st | 8.0 | 6.0 | 0.720 | 8.0 | 5.0 | 0.208 | 8.0 | 7.0 | 0.757 | 8.0 | 5.0 | 0.146 | 8.0 | 6.0 | 0.479 |
| 2nd | 8.0 | 6.0 | 8.0 | 6.0 | 8.0 | 6.0 | 8.0 | 6.0 | 5.0 | 6.0 | ||||||
| Meiboscale (grade) |
1st | 1.0 | 0.5 | 0.020 | 1.0 | 0.5 | 0.126 | 1.0 | 0.5 | 0.185 | 1.5 | 1.0 | 0.261 | 1.5 | 1.0 | 0.596 |
| 2nd | 1.5 | 1.0 | 1.5 | 1.0 | 1.5 | 1.0 | 1.5 | 1.5 | 1.5 | 1.0 | ||||||
| PB | 1st | 3.0 | 5.0 | 0.004 | 4.0 | 5.0 | 0.331 | 3.0 | 5.0 | 0.051 | 3.0 | 4.0 | 0.176 | 3.0 | 4.0 | 0.029 |
| 2nd | 2.0 | 4.0 | 3.0 | 5.0 | 2.0 | 3.0 | 2.0 | 3.0 | 1.0 | 3.0 | ||||||
| PB (%) | 1st | 62.5 | 60.8 | 0.002 | 62.5 | 61.6 | 0.048 | 60.0 | 62.6 | 0.028 | 63.1 | 58.5 | 0.890 | 50.0 | 60.1 | 0.110 |
| 2nd | 50.0 | 63.3 | 50.0 | 57.5 | 48.3 | 62.3 | 66.7 | 63.3 | 33.3 | 77.2 | ||||||
| TB | 1st | 6.0 | 6.0 | 0.901 | 7.0 | 7.0 | 0.389 | 6.0 | 6.0 | 0.905 | 6.0 | 5.0 | 0.459 | 6.0 | 6.0 | 0.506 |
| 2nd | 6.0 | 7.0 | 7.0 | 7.0 | 6.0 | 7.0 | 5.0 | 6.0 | 4.0 | 6.0 | ||||||
| Schirmer test (mm) | 1st | 4.0 | 5.0 | 0.003 | 4.0 | 5.0 | 0.021 | 4.0 | 5.0 | 0.296 | 4.0 | 4.0 | 0.651 | 4.0 | 5.0 | 0.015 |
| 2nd | 3.0 | 5.0 | 3.0 | 5.0 | 4.0 | 5.0 | 4.0 | 4.3 | 2.0 | 4.0 | ||||||
| FTBUT (sec) | 1st | 3.0 | 1.0 | 0.555 | 3.0 | 1.0 | 0.575 | 3.0 | 1.0 | 0.846 | 3.0 | 1.0 | 0.881 | 3.0 | 1.0 | 0.678 |
| 2nd | 3.0 | 1.0 | 3.0 | 2.0 | 3.0 | 1.0 | 3.0 | 1.0 | 2.0 | 1.0 | ||||||
| SPK (grade) | 1st | 0.0 | 0.0 | 0.187 | 0.0 | 0.0 | 0.030 | 0.0 | 0.0 | 0.815 | 0.0 | 1.0 | 0.647 | 0.0 | 0.0 | 0.672 |
| 2nd | 0.0 | 1.0 | 0.0 | 1.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | ||||||
DM: dermatochalasis; IQR: interquatile range; MGE: number of expressible meibomian glands; OSDI (A): subtotal of the frequency of symptoms; OSDI (B): subtotal of the frequency of activity limitation; OSDI (C): subtotal of the frequency of environmental factors triggering discomfort; LLT: average lipid-layer thickness; PB: number of partial blinks; B (%): partial blink rate; TB: total number of blinks; FTBUT: fluorescein tear-film break-up time; SPK: superficial punctate keratitis; p: statistical significance using the Friedman tes.