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. 2022 Apr 29;13:889694. doi: 10.3389/fmicb.2022.889694

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Copyright © 2022 Yang, Zhang, Xu, Adeel, Lu, Chen, Shen, Li and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The specific relationships of fungal genus and immune-related factors. (A) The relative tissue mRNA level of 10 immune cytokines in HC and GC groups. The differences are calculated by Mann-Whitney U test (***p < 0.001; ****p < 0.0001). (B) Correlation analysis of the top 20 differential genera and 10 immune-related factors between the two groups according to the Spearman's correlation analysis. The correlation effect is indicated by a color gradient from blue (negative correlation) to red (positive correlation). Correlation coefficients and p-values (*p < 0.05; **p < 0.01) are shown.