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. 2022 May 9;23(9):5270. doi: 10.3390/ijms23095270

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of compound A on expression levels of T_H2, T_H17, and T_H1 cytokines in the lung tissues of OVA-induced asthma in FFA4-WT mice. Analysis of mRNA expression of T_H2 (IL-4, IL-5, and IL-13), T_H17 (IL-17A), and T_H1 (IFN-γ) cytokines in the lung tissues of OVA-induced and compound A-treated FFA4-WT mice. Relative mRNA levels of cytokines were quantified as ratios to GAPDH transcript levels. (A) IL-4, (B) IL-5, (C) IL-13, (D) IL-17A, and (E) IFN-γ. The results are presented as mean ± SEM (n = 5). ** p < 0.01, *** p < 0.001 vs. the PBS-treated group, # p < 0.05, ## p < 0.01, ### p < 0.001 vs. the OVA-treated group.