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. 2022 Apr 27;11(9):1467. doi: 10.3390/cells11091467

Figure 9.

Figure 9

Rac1 activation mediates the increased wound healing in P-cadherin deficient IEC monolayers. (A) G-LISA assay shows Rac1 activation in P-cadherin knockout HCA-7 cells. Control and P-cadherin knockout HCA-7 cell monolayers were wounded and allowed to migrate in the presence of either vehicle, or Rac1 inhibitor, EHT 1864 (50 μM). Representative pictures of wounded monolayers (B) and quantification of wound closure (C) are shown. Means ± SE (n = 4); ** p < 0.01, *** p < 0.005. Scale bar, 100 μm. The results shown are representative of two independent experiments.