TABLE 3.

MC4R DNA methylation levels on the maternal and fetal side of placenta normoglycemic (NGT) and gestational diabetes (GDM) women expressed as mean and standard deviation (SD). Mean differences were evaluated by unpaired t-test.

Characteristics	NGT (n = 27)	GDM (n = 33)	p-value
Maternal side of placenta
CpG1	4.40 (3.9)	5.40 (4.8)	0.379
CpG2	14.6 (11.0)	17.6 (10.7)	0.296
Maternal Mean Methylation levels	9.50 (7.2)	11.5 (7.0)	0.285
Fetal side of placenta
CpG1	6.4 (4.30)	4.7 (4.6)	0.141
CpG2	18.9 (10.0)	13.2 (9.5)	0.028
Fetal Mean Methylation levels	12.7 (6.7)	8.95 (6.3)	0.033

Statistically significant values are in bold. ⁺p-value derived from unpaired t-test.