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. 2022 Apr 29;27(9):2841. doi: 10.3390/molecules27092841

Figure 3.

Figure 3

SARS-CoV-2 3C-like main protease inhibition of piperine (1), piperic acid (2), and N-aryl amide analogs of piperine 3–5. Compounds 1–5 and rutin (positive control) were tested at 100 μM.