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. 2022 Apr 23;23(9):4688. doi: 10.3390/ijms23094688

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Isolated perfused hearts after LPS. Working heart preparations of wild type (WT) and PP2A overexpressing mouse hearts 3 days after intraperitoneal application of LPS (25 mg/kg) or NaCl solution as control. (A) Heart rate, (B) maximum left ventricular pressure (LVP), (C) maximum rate of left ventricular pressure development (+dP/dt), (D) maximum rate of left ventricular pressure decline (−dP/dt), (E) activity of NADPH oxidase in cardiac tissue from WT or PP2A-TG. Numbers in brackets indicate the number of experiments ^★ p < 0.05 vs. WT; # p < 0.05 vs. control (Ctr).