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. 2022 Apr 23;23(9):4688. doi: 10.3390/ijms23094688

Figure 6.

Figure 6

Ischemic cardiac function in isolated perfused hearts from wild type hearts (WT) and heart with cardiac specific overexpression of the catalytic subunit of protein phosphatase 2A (PP2A-TG). Contraction parameters were assessed under basal conditions and 120 min after ischemia. Heart rate is depicted as beats per minute (BPM) under (A), maximum left ventricular pressure as milli meter mercury column (mm Hg) (B) as LVPs, maximum first derivative of pressure in left ventricle in millimeter mercury column per second (mmHg/s) in the ordinate of (C), minimum first derivative of pressure in left ventricle in millimeter mercury column per second (mmHg/s) in the ordinate of (D), open bars indicated basal perfusion conditions and filled bars indicate values at the end of the ischemia. Numbers in bars depict the numbers of experiments in hearts from WT or PP2A-TG. ★ p < 0.05 vs. WT, # p < 0.05 vs. basal conditions.