Figure 3.
Effect of Emorsan® Gel treatment on IL-1β expression after WH. Epidermal tissues collected from WH-vehicle injured mice showed positive IL-1β immunostaining (C,C1,G,G1,I), compared to the sham-treated mice 6 days and 12 days after WH induction (A,A1,B,B1,E,E1,F,F1,I). Emorsan® topical administration reduced IL-1β expression in a significant way (D,D1,H,H1,I). Data are representative of at least three independent experiments. Values are means ± SEM. One-Way ANOVA test. *** p < 0.001 vs. corresponding Sham; ### p < 0.001 vs. corresponding WH; °° p < 0.01 vs. WH+Emorsan 6 days; ND: not detectable.