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. 2022 Apr 24;23(9):4708. doi: 10.3390/ijms23094708

Figure 7.

Figure 7

Effect of Emorsan® Gel treatment on VEGF expression after WH. Mice of the vehicle group showed a marked positive immunostaining for VEGF after 6 days of WH induction (C,C1,I) compared to sham mice both on day 6 and day 12 after WH induction (A,A1, B,B1,E,E1,F,F1, I). In the vehicle group, such positive immunostaining was even more intense 12 days after WH induction (G,G1,I). Contrarily, Emorsan®-treated mice revealed a modulation of VEGF levels, which were increased 6 days after WH induction (D,D1,I), and decreased 12 days after the start of the experiment (H,H1,I). Data are representative of at least three independent experiments. Values are means ± SEM. One-Way ANOVA test. *** p < 0.001 vs. corresponding Sham; ### p < 0.001 vs. corresponding WH; °°° p < 0.001 vs. WH+Emorsan 6 days.