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. 2022 Apr 29;23(9):4948. doi: 10.3390/ijms23094948

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Transcriptome and MeRIP sequencing of the control and Cd groups. (A) Heat map results revealed differential transcript levels after Cd treatment. (B) Volcano map showed the differentially expressed mRNAs in the control and Cd groups. (C,D) GO and KEGG analyses results revealed the enrichment of differential genes in the control and Cd groups. (E) The HOMER motif analysis results revealed the m⁶A motif in granulosa cells. (F) Density distribution of m⁶A enrichment across mRNA transcriptome in granulosa cells. (G) Distribution of peaks with significant differences in the RNA expression and m⁶A modification level in the control and Cd groups.

Transcriptome and MeRIP sequencing of the control and Cd groups. (A) Heat map results revealed differential transcript levels after Cd treatment. (B) Volcano map showed the differentially expressed mRNAs in the control and Cd groups. (C,D) GO and KEGG analyses results revealed the enrichment of differential genes in the control and Cd groups. (E) The HOMER motif analysis results revealed the m⁶A motif in granulosa cells. (F) Density distribution of m⁶A enrichment across mRNA transcriptome in granulosa cells. (G) Distribution of peaks with significant differences in the RNA expression and m⁶A modification level in the control and Cd groups.