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. 2022 Apr 25;11(9):2415. doi: 10.3390/jcm11092415

Table 2.

References values of soluble α-Klotho serum levels using an enzyme-linked immunosorbent assay in healthy adults aged 18–85 years.

α-Klotho (pg/mL)
Mean SD Reference Interval
(5th–95th Percentile)
All (n = 346) 813.8 461.2 340.1 1672.5
 Men (n = 143) 728.3 412.0 323.4 1541.8
 Women (n = 203) 874.0 485.0 385.4 1750.8
18–34.9 years (n = 167) 932.6 575.6 392.6 2291.8
 Men (n = 57) 850.9 566.4 341.2 2282.8
 Women (n = 110) 975.9 578.3 427.2 2345.5
35–54.9 years (n = 88) 796.7 317.4 330.2 1364.6
 Men (n = 41) 733.9 249.6 324.6 1228.3
 Women (n = 47) 851.5 360.2 312.6 1420.0
55–85 years (n = 91) 612.1 198.2 235.8 918.6
 Men (n = 45) 567.9 192.5 190.4 851.5
 Women (n = 46) 655.5 196.2 260.4 934.4

Data are expressed as means, standard deviations (SD), and reference values (5th–95th percentile).